Progestin IUDs and Hormonal Effects

Dr. Liz Bartman

Did you know that women using Progestin IUDs may face a greater risk of experiencing high androgen symptoms, including acne, hair loss, and excess facial hair growth?

Progestin IUDs

Here are some key insights regarding the risks associated with different types of Progestin IUDs:

  • Acne Risk (Highest to Lowest): Kyleena > Mirena > Skyla
  • Alopecia and Hirsutism Risk (Highest to Lowest): Mirena > Kyleena > Skyla
  • Minimal Risk: Liletta IUD

These effects are linked to how Progestin IUDs modulate androgen receptors after insertion.

Progestin IUD & Mood Swings

Additionally, Progestin-containing IUDs have been associated with a greater risk of mood changes and depression, particularly among younger women. While the mental and emotional stress of an unwanted pregnancy often outweighs these risks, it is important to provide counseling and tailored support to patients using hormonal birth control to help address both physical and emotional well-being.

Progestin IUDs can also impact mineral absorption, leading to decreased levels of folate, vitamin B12, calcium, and magnesium.